Facts about Duchenne Muscular Dystrophy:
Worldwide the incidence
of Duchenne Muscular Dystrophy (DMD) is 1:3500 male births. In
70% of the cases females are the carriers of the disease, but only
rarely develop symptoms themselves. If the female is the
carrier, there is a 50% chance per male birth that her male
offspring will have Duchenne and a 50% chance that her female
offspring will be carriers. Duchenne Muscular Dystrophy is the
most common, inherited lethal disorder in children.
Prognosis: Duchenne
Muscular Dystrophy is a disorder of normal muscle growth resulting
in a rapidly progressive loss of function. Three distinct phases are
associated with DMD:
1. Transitional Phase
(6–12 years): Demonstrates marked postural adjustments,
frequent falls, increasing muscle weakness and functional
loss.
2. Loss of Ambulation
(8–14 years): Typically children with DMD lose the ability to
walk between 9 and 12 years of age.
3. End Stage (15
years+): Respiratory problems are associated with end stage.
Infections can lead to death due to poor respiratory function.
Assisted ventilation may be used to improve respiratory
mechanics. Cardiac function can be affected. Boys with
Duchenne typically do not live beyond the age of
20.
Treatment: There
is no current cure for DMD. Treatment for DMD is aimed at
managing the symptoms in an effort to optimize the quality of
life.
Prevention:
Genetic counseling is advised if there is a family history of the
disease. Discovery of the genetic cause of DMD has
revolutionized diagnosis and genetic counseling. Duchenne
Muscular Dystrophy can be detected with approximately 95% accuracy
with prenatal testing. Unfortunately, Duchenne Muscular
Dystrophy will never successfully be prevented by genetic counseling
because new mutations occur spontaneously and with high frequency.
This means that every man or woman can be a carrier of the
disease.
Our Goal: The
Grant C. Alexander Scholarship Foundation’s objective is to increase
awareness concerning DMD. Our hope is that everyone will be
screened for the possibility of being a potential carrier of
Duchenne’s before beginning a family. Prevention of DMD is a
matter of knowing about the possibilities before birth.
Duchenne, while considered a very difficult and complex disease,
serves as a testing ground for the development of new
technologies. We hope and pray for a cure.
The scholarship is a
means to inform applicants and their parents of this tragic disease
that attacks the most innocent of victims.
ABS Business Products
has sponsored this scholarship because of a personal relationship
with Grant C. Alexander and his family. Our belief is that
your heart is your most important muscle.
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